Lizakbar's evolution line is a playful rendition of the stereotype that Muslims are terrorists, as suggested by events such as 9/11 and the Syrian Civil War. Its tail is based on the fuse of a bomb. It may also reference the "Allahu akbar" meme. Its appearance is based on the bearded lizard, though it has many humanoid features, and the attire commonly worn by both Muslims and bombers.
Lizakbar is a combination of the word lizard and the Arabic phrase Allahu akbar, which translates as "God is great" or "God is magnificent". Allahu akbar has been used as a battle cry for Muslims for as far back as the Crusades. However, in this case, it is associated with Islamic extremist terrorists, who have been known to shout the phrase before a suicide bombing.